for his work on ribonucleaseandfor their contribution to the understanding of the connection between chemical structure and catalytic activity of the ribonuclease molecule
for their elucidation of the enzymatic mechanism underlying the synthesis of adenosine triphosphateandfor his discovery of an ion-transporting enzyme, Na+, K+ -ATPase
... and the formation of the Lutheran Schmalkaldic League, and Charles delegated increasing responsibility for Germany to his brother Ferdinand while he concentrated on problems ...